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Manfred Morari speaks in Distinguished Lecture Series at the University of Utah

Control of anesthesia

The strongest impact from the use of automatic control will not be in areas where control has been used for decades and any advances will only be incremental. It will be in areas where entirely new avenues for the application of control were created through the entrance of an enabling new technology, for example, the development of a new sensor, a new actuator or simply the inexpensive enormous computer power which we have now at our disposal. The discoveries and the developments in biology, chemistry, physics and electronics are creating a revolution in diagnosis and practice of medicine. Therefore, we expect unprecedented opportunities for control to emerge in biomedical engineering. As an illustrative example we will use anesthesia, where new measures of depth of consciousness and analgesia have emerged recently. They have been used in feedback control and applied in the operating room by our group for the first time. We will discuss the major challenges that are in modeling (limited physiological understanding, large variability), signal conditioning (noisy/faulty measurements, outlier detection), controller design (constraints, fault tolerance, prioritized objectives), controller implementation (user interface, safety-critical real-time operating system) and acceptance by the medical community.


Mar 23, 2004   
Contact Person:

Manfred Morari