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TCI for multiple drugs: the two dimensional user interface approach

Author(s):

A. Caruso, M. Morari, T. Bouillon, M. Luginbühl, P.M. Schumacher
Conference/Journal:

First World Congress of Total Intravenous Anaesthesia - TIVA TCI, Venice, Italy
Abstract:

No integrated platform has emerged that supports TCI dosing of several drugs. Separate TCI pumps for propofol and remifentanil or alfentanil cannot account for the 15%-reduced remifentanil/alfentanil elimination caused by propofol. These requirements were defined for a combined TCI system: 1) interacting pharmacokinetics are considered for model calculation of TCI dosing profiles, 2) drug dosing can be changed for all pumps through a single point of interaction, 3) dosing is based on a relevant endpoint for anesthesia (effect steering), 4) changing the hypnotic/opioid concentration ratio shall not unintentionally change depth of anesthesia. A prototype was built using MATLAB to verify results in simulations.

Year:

2007
Type of Publication:

(01)Article
Supervisor:

M. Morari

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% Autogenerated BibTeX entry
@InProceedings { CarEtal:2007:IFA_2851,
    author={A. Caruso and M. Morari and T. Bouillon and M. Luginb{\"u}hl and P.M.
	  Schumacher},
    title={{TCI for multiple drugs: the two dimensional user interface
	  approach}},
    booktitle={First World Congress of Total Intravenous Anaesthesia -
	  TIVA TCI},
    pages={},
    year={2007},
    address={Venice, Italy},
    month=sep,
    url={http://control.ee.ethz.ch/index.cgi?page=publications;action=details;id=2851}
}
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