Note: This content is accessible to all versions of every browser. However, this browser does not seem to support current Web standards, preventing the display of our site's design details.


TCI for multiple drugs: the two dimensional user interface approach


A. Caruso

First World Congress of Total Intravenous Anaesthesia - TIVA TCI, Venice, Italy

No integrated platform has emerged that supports TCI dosing of several drugs. Separate TCI pumps for propofol and remifentanil or alfentanil cannot account for the 15%-reduced remifentanil/alfentanil elimination caused by propofol. These requirements were defined for a combined TCI system: 1) interacting pharmacokinetics are considered for model calculation of TCI dosing profiles, 2) drug dosing can be changed for all pumps through a single point of interaction, 3) dosing is based on a relevant endpoint for anesthesia (effect steering), 4) changing the hypnotic/opioid concentration ratio shall not unintentionally change depth of anesthesia. A prototype was built using MATLAB to verify results in simulations.


Type of Publication:


M. Morari

File Download:

Request a copy of this publication.
(Uses JavaScript)
% No recipe for automatically generating a BibTex entry for (06)Talk
Permanent link