Note: This content is accessible to all versions of every browser. However, this browser does not seem to support current Web standards, preventing the display of our site's design details.


Feedback control in conscious sedation - integrating sensor, controller and actuator on xPC platform


Philip Jonas

Semester/Bachelor Thesis, FS 08

In conscious sedation procedures, the patient is sedated but retains the ability to breathe spontaneously. Drug induced ventilatory depression represents a dangerous side effect of sedation, possibly leading to hypoventilation and subsequent hypoxia. We advocate the use of an automatic controller to manage drug infusion during conscious sedation based on measurements of transcutaneous CO2 partial pressure. For a clinical proof of concept study we need to integrate the existing controller software on a real time platform interfacing actual sensors and actuators. The simulation environment was implemented in a Matlab/Simulink environment. The real time platform is an xPC targetbox capable of running most Matlab/Simulink code. The aim of this semester thesis is to validate existing driver code for sensors and actuator and to establish and streamline an integration process of the controller software for real time execution on the xPC targetbox and to verify overall system performance and stability. The controller software written in Matlab/Simulink has to remain the master code base at all times and the above mentioned process has to guarantee a quick and effortless transfer into the real time environment. A good knowledge of the Matlab/Simulink environment is a must, xPC experience is a plus. An important part of the work will be performed on the premises of our cooperation partner at the University Hospital in Bern.

Supervisors: Prof. M. Morari, Dr. A. Caruso


Type of Publication:

(13)Semester/Bachelor Thesis

M. Morari

No Files for download available.
% Autogenerated BibTeX entry
@PhdThesis { Xxx:2008:IFA_3187
Permanent link