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Provocation discography -Modeling, simulation and implementation for clinical testing


Stephanie Stockar

Semester/Bachelor Thesis, FS 08

The provocation discography is the physiologic test to diagnose patients with chronic low back pain. In general, painful internal disc degeneration may not have external features. The contour of the disc remains normal impeding the correct evaluation of disc disruption using Computed tomographic scanning (CT) or Magnetic resonance imaging (MRI). The discography remains, therefore, particularly useful in problematic cases which are not definitively diagnosed by non-invasive procedures. This procedure, unfortunately, is not accepted as standardized for various reasons. To this end, it has been decided to propose a clinical study to present a novel method to perform the provocation discography in order to deliver objective and reproducible results for the diagnostic assessment of discogenic pain. The aim of this thesis is to provide an appropriate simulation environment for the development and testing of the control algorithm. In this work a model for the intervertebral disc with or without lesions, a model for the infusion system and a supervising algorithm controlling the intradiscal pressure have been computed and validated with experimental data. The obtained results show that the disc can be modeled omitting the dynamic of the system and that a PI controller is able to regulate the intradiscal pressure in both physiological or a pathological disc.

Supervisors: Prof. M. Morari, Dr. A. Caruso


Type of Publication:

(13)Semester/Bachelor Thesis

M. Morari

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% Autogenerated BibTeX entry
@PhdThesis { Xxx:2008:IFA_3188
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