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Development of a closed-loop neural prosthesis for vestibular disorders


J. DiGiovanna, W. Gong, Csilla Harburcakova, Vinzenz Kögler, J. Carpaneto, Vincenzo Genovese, D. Merfeld, Andreas Demosthenous, Jean-Philippe Guyot, Klaus-Peter Hoffmann, Alain Berthoz, M. Morari, S. Micera

Journal of Automatic Control, vol. 20, pp. 27-32

Vestibular disorders can cause severe problems including spatial disorientation, imbalance, nausea, visual blurring, and even cognitive deficits. The CLONS project is developing a closed-loop, sensory neural prosthesis to alleviate these symptoms [1]. In this article, we outline the different components necessary to develop this prosthetic. A short version of this work was presented in the NEUREL 2010 [1]. Conceptually, the prosthesis restores vestibular information based on inertial sensors rigidly affixed to the user. These sensors provide information about rotational velocity of the head; the prosthetic then transfers the information to the vestibular nerve via electrical stimulation. Here we present a project overview, development details, and summarize our progress in animal models and selected human volunteers.


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% Autogenerated BibTeX entry
@Article { DiGEtal:2010:IFA_3716,
    author={J. DiGiovanna and W. Gong and Csilla Harburcakova and Vinzenz
	  K{\"o}gler and J. Carpaneto and Vincenzo Genovese and D. Merfeld and Andreas Demosthenous and Jean-Philippe Guyot and Klaus-Peter
	  Hoffmann and Alain Berthoz and M. Morari and S. Micera},
    title={{Development of a closed-loop neural prosthesis for
	  vestibular disorders}},
    journal={Journal of Automatic Control},
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