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A real-time platform for studying the modulatory capacity of epidural stimulation after spinal cord injury

Author(s):

E. Martin Moraud, Nikolaus Wenger, Jerome Gandar, J. DiGiovanna, Pavel Musienko, Gregoire Courtine, S. Micera
Conference/Journal:

IEEE EMBS Conference on Neural Engineering, San Diego, CA, USA, no. 1, pp. 1449-1452
Abstract:

Epidural electrical stimulation (EES) showed promises to improve standing and walking after neurological disorders. To date, EES has been delivered continuously, although time-dependent stimulations would likely be more efficient to activate specific subsets of sensorimotor circuits with the appropriate timing. To address this issue, we developed a real-time stimulation platform that allows to trigger EES during pre-defined phases of the gait cycle in freely walking rats. We leveraged this platform to demonstrate the ability of time-dependent EES to modulate key aspects of locomotor kinematics in rats with complete spinal cord transection. This platform will support the development of personalized stimulation strategies that can be tailored to the need of individual subjects.

Year:

2013
Type of Publication:

(01)Article
Supervisor:

S. Micera

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% Autogenerated BibTeX entry
@InProceedings { MorEtal:2013:IFA_4599,
    author={E. Martin Moraud and Nikolaus Wenger and Jerome Gandar and J.
	  DiGiovanna and Pavel Musienko and Gregoire Courtine and S. Micera},
    title={{A real-time platform for studying the modulatory capacity
	  of epidural stimulation after spinal cord injury}},
    booktitle={IEEE EMBS Conference on Neural Engineering},
    pages={1449--1452},
    year={2013},
    address={San Diego, CA, USA},
    month=nov,
    url={http://control.ee.ethz.ch/index.cgi?page=publications;action=details;id=4599}
}
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