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Online optimisation and feedback control of a SMB plant: a LabVIEW Matlab procedural implementation


M. Lawrence, G. Erdem, S. Abel, M. Morari, M. Mazzotti, M. Morbidelli, L. Jensen

Munchen, Virtuelle Instrumente in der Praxis, pp. 241-247, Begleitband zum Kongress VIP 2004. ISBN 3-7785-2932-3

The Simulated Moving Bed (SMB) is a continuous multi-column chromatographic process that has become an attractive technology for complex separation tasks that are regularly encountered in the areas of pharmaceuticals, fine chemicals and biotechnology. Even though economic optimality of the SMB process has attracted significant amount of attention, operation of the SMB units at their optimal operating conditions is still an open issue due to the absence of applicable feedback control schemes. Recently, we have developed an on-line optimisation based feedback control scheme that can deliver the full economic potential of the SMB technology despite disturbances and uncertainties. This paper focuses on the integration of LabVIEW features with the developed feedback control scheme in order to verify the experimental feasibility of the control concept on the existing SMB plant. The system is designed such that LabVIEW runs the SMB plant, with on-line optimisation based feedback control scheme undertaken in MATLAB interfaced with a commercial solver, i.e., ILOG CPLEX 7.0. The designed system runs the LabVIEW and the feedback control codes on separate computers and can perform all the given tasks within one second, satisfying timing issues required for the optimal control and operation of the plant.


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% Autogenerated BibTeX entry
@Article { LawEtal:2004:IFA_52,
    author={M. Lawrence and G. Erdem and S. Abel and M. Morari and M. Mazzotti and M.
	  Morbidelli and L. Jensen},
    title={{Online optimisation and feedback control of a SMB plant: a
	  LabVIEW Matlab procedural implementation}},
    journal={Virtuelle Instrumente in der Praxis},
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